Titles

  • Assistant Professor, Université de Montréal, Department of Radiology, Radiation Oncology and Nuclear Medicine
  • Regular Researcher, Centre de recherche du Centre hospitalier de l’Université de Montréal
  • Research member, Institut du cancer de Montréal

Research Angle

  • Ultrasound imaging with contrast agents
  • Targeted anti-cancer therapies using ultrasound
  • Targeted drug delivery
  • Microbubble/Cell Interactions and Microfluidics
  • Provascular therapy for radiosensitization of solid tumors
  • Vascular permeabilization and immunotherapy

Laboratory Team

  • Sepideh Jahangiry, étudiante Ph.D.
  • Marie Amate, étudiante Ph.D.
  • Kishan Italiya, Post-doctorant
  • Samuel Bourdages M.Sc.

Recent Publications

  1. Yu F.T.H., Chen X., Wang J., Qin B. and Villanueva F.S., «Low intensity ultrasound mediated liposomal doxorubicin delivery using polymer microbubbles», Mol. Pharm, 4;13(1):55-64, 2016.
  2. Yu F.T.H., Chen X, Straub A. and Pacella J.J., The Role of Nitric Oxide during «Sonoreperfusion of Microvascular Obstruction», Theranostics, 7(14) :3527-3538, 2017
  3. Istvanic F., Yu G.Z., Yu F.T.H., Powers J., Chen X. and Pacella J.J., «Sonoreperfusion therapy for microvascular obstruction: A step toward clinical translation», Ultrasound Med Biol. 2020;46:712-720.
  4. Amate M., Goldgewicht J., Sellamuthu B., Stagg J. and Yu F.T.H., «The effect of ultrasound pulse length on microbubble cavitation induced antibody accumulation and distribution in a mouse model of breast cancer», Nanotheranostics. 2020;4:256-269
  5. Grygorczyk, R, Boudreault F., Ponomarchuk O., Tan J.J., Furuya K, Goldgewicht J., Démèze K. F., and Yu F., Lytic release of cellular ATP: physiological relevance and therapeutic applications, Life Life, 11(7):700, 2021
  6. Cloutier G., Destrempes F., Yu F.T.H., Tang A., Quantitative ultrasound imaging of soft biological tissues: A primer for radiologists and medical physicists, Insights Imaging,12(1):127, 2021
  7. Michon S., Rodier F. and Yu F., Targeted Anti-Cancer Provascular Therapy Using Ultrasound, Microbubbles and Nitrite to Increase Radiotherapy Efficacy, Bioconjugate Chem, 2022, in press 

Pubmed Page

https://pubmed.ncbi.nlm.nih.gov/?term=francois+yu+ultrasound

Email address for application

Francois.yu@umontreal.ca

Biography

Dr. Yu received his B.Sc. in Electrical Engineering in 2001 from École Polytechnique de Montréal and his PhD in Biomedical Engineering from Université de Montréal in 2010. Dr. Yu specializes in high frequency ultrasound imaging of diseases associated with rheological disorders and in the use of microbubbles (ultrasound contrast agent) in imaging and therapy for targeted theranostic applications in oncology and cardiology.